A. Write a summary of the significance and background of a healthcare problem by doing the following: 1. Describe a healthcare problem that can be used to develop a PICO question. You may choose a topic and select articles focusing on one of the following topics: falls and fall prevention, pain management in children, opioid abuse, hepatitis C, catheter-associated urinary tract infections, and hand hygiene and infections in hospitals. 2. Explain the significance of the problem from part A1. 3. Describe the current healthcare practices related to the problem from part A1. 4. Discuss how the problem affects the organization and patients cultural background (i.e., values, health behavior, and preferences). B. Complete a literature review by searching for a total of seven articles consisting of five research articles and two non-research articles related to the healthcare problem from part A1, and describe the search strategy you used to conduct the literature review by doing the following: 1. Discuss two research evidence sources and two nonresearch evidence sources that you considered. Note: Please do not use the same primary author for more than two articles. Articles must not be more than five years old. C. Use your research articles to develop a PICO (patient/population, intervention/indicator, comparison/control, and outcome) question based on the topic. D. n/a E. Recommend a practice change that addresses the PICO question, using the evidence collected in the attached Evidence Matrix. You must use all five research articles from the Evidence Matrix attachment to support this recommendation via in-text citations. F. Describe a process for implementing the practice change from part E in which you do the following: 1. Explain how you would involve three key stakeholders in the decision to implement the recommendation from part E. 2. Describe two specific barriers you may encounter when implementing the practice change from part E in the nursing practice setting. 3. Identify two strategies that could be used to overcome the barriers described in part F2. 4. Identify one indicator to measure the outcome (the O in PICO question) of the recommended change practice from part E. G. Acknowledge sources, using APA-formatted in-text citations and references, for content that is quoted, paraphrased, or summarized. H. Demonstrate professional communication in the content and presentation of your submiss
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