critical appraisal

Write 6 pages thesis on the topic critical appraisal. The author was very perfect in that he gave the whole project briefing. He gave us his objectives, methodologies, and his findings. However, the part failed to give us any hypothesis that would be tested. Any scientific work should have both null and alternative hypotheses that would be statistically analyzed for their significance.The introduction is very straight to the point and giving vital information on cancer (&nbsp.Jones, 2003). In fact, the section is giving the background of the research. The setting of the context enables us to understand more ideas that we had little information about. The functions of the MMPs are clearly explained in their functionality in metastasis. The author even classifies the different forms of MMPs to give us an insight into why he specifically chose the MT4-MMP ad, not others (Yeung, Sieracki, and Marshall, 2009). He classifies two MMPS different claiming that they are linked to the membrane through a glycosyl-phosphatidylinositol (GPI). The two compounds are MT4 and MT6-MMPs. He further continues to notify us that our compound of interest is found in the brain, colon, lung, uterus, and reproductive organs. Their location was the reason the lymphatic system trace of MT4-MMP would very easy and simple within the mice.Every idea is supported by reference to validate the data. Previous studies have been incorporated and compared to enrich the context. For example, comparisons with other forms of works are in relation and agreement that MMPs are involved in metastasis of tumor cells (Piyush, 2013). However, there has been contradicting information from various science fields concerning MMPs, Extra Cellular Matrix degradation, and cancer cell division. Some of the studies have associated MMPs inhibition to synthetic and natural inhibitors hence inhibition of the cell invasion. However, abnormal expressions of various forms of MMPPs have been correlated with pathological conditions in arthritis, tumor cell invasion, and the general metastasis. Whenever a substance will be used to stimulate a given process, then the same substance can be used in the inhibition of the process (Yeung et al., 2012). In this case, if the presence of a substance has a positive effect, then its absence will have a negative effect too. In our case, if the MMP’s presence is being involved in metastasis, then its absence will mean that there is no metastasis. The fact is complementing with the statement that MMPs promote the growth of cancer cells by helping in cleavage of the insulin growth factor binding protein abbreviated as (IGF-BP). Moreover, the MMPs can inhibit cancer growth by liberating growth factors such as ? – (TGF- ?) from the TGF- ? complex (Egeblad and Werb, 2002).

Assignments Ace
Order NOW For A 10% Discount!
Pages (550 words)
Approximate price: -

Why Assignmentsace?

Top Quality and Well-Researched Papers

We offer top-quality and well-researched assignment papers at low prices. We believe in offering the best quality services as we care about your grades, academic performance, and success. Our writers range from masters and Ph.D. graduates to professors. Our panel of expert academic writers does not rest until they are 100% sure your essay will score you an A+ only.

Professional and Experienced Academic Writers

Our writing company has the best panel of experienced academic and business writers. Our writers have experience of up to 9 years in the writing industry. They will go the extra mile to make sure you are handing in a quality A+ paper. If you are a student searching for any academic help, I advise you to seek for our experts' help.

Free Unlimited Revisions

Our clients frequently ask if they will be liable to free revisions once they place an assignment order with us. However, how many times you ask for revisions, our academic experts will help you. Either way, there is no need to worry as we provide free revisions. We are always after our clients’ satisfaction, and we are very proud to say that all our clients are satisfied with our writing services.

Prompt Delivery and 100% Money-Back-Guarantee

We are strict when it comes to assignments deadlines. We make sure our writers keep in mind the assignment delivery time. Because we care about clients, we go that extra mile to make sure you do not face those consequences. Whatever the deadline, we promise our clients a prompt delivery.

Affordable Prices

Are our charges too cheap for you to believe? Here at Assignments Ace, we offer quality assignment help at affordable prices. Our prices are substantive to cater to all students. Every time you place your assignment order with us, you are guaranteed a 15% discount.In addition, new clients enjoy a discount of 30% when placing their first order with us.

Customer Support 24/7

Do you have any queries for us? Or do you want to consult with our expert academic writers? Go ahead and contact us. We have 24/7 online friendly customer service. Whatever time of the day or night, we are always available for you. You can chat with us via our online chat services or contact us via our email,

Try it now!

Calculate the price of your order

We'll send you the first draft for approval by at
Total price:

How it works?

Follow these simple steps to get your paper done

Place your order

Fill in the order form and provide all details of your assignment.

Proceed with the payment

Choose the payment system that suits you most.

Receive the final file

Once your paper is ready, we will email it to you.

Our Services

Our assignments help website is the most internationally sought-after site because we offer a wide range of top-quality services at low prices. Our proud history as an assignment help company stretches back nine years. We do offer Top Quality, Well-Researched Papers and Online classes to help students internationally. We do both of these things at cheap affordable prices by offering up to a 30% discount.


Essay Writing Services

Writing an essay is one of the most tedious tasks that require a lot of concentration and research. Writing an essay takes hours and even up days. We offer the best custom writing service and have your best interests in mind. Most online writing industries do not have qualified writers and are just after your money. Worry less, our writers who have enough experience are ready to give you the help you need. Our writers are carefully selected and undergo some tests to prove their professionalism.


Admission Papers

Are you applying for a college? We help students join their dream college by writing for them strong admission papers that showcases their qualities and personalities. An admission essay is an essay or other written statement by a candidate, often a potential student enrolling in a college, university, or graduate school. We utilize statements of purpose, personal statements, and personal essays to make a compelling case by stating your leadership activities, education, accomplishments, and professional background.


Editing and Proofreading

We offer an abundance of online proofreading and editing services for our clients. By definition, proofreading is the final surface-level check done on a document. Other academic writing companies offer editing and proofreading as separate services. At our assignment help website, we offer editing and proofreading services as one complete package at affordable cheap prices. Grab your 30% Coupon if you order today!!!


Business Paper

Are you a student pursuing an MBA in business, no need to look any further? We offer the best assignment help as we have the top niche MBA business writers who will give you A+ assignments. Over the years, our experts have helped students accomplish their academic dreams. We have helped thousands of students complete their business assignments with confidence.Grab your 30% Coupon if you order today!!!